1MaginAZN's video: In 5 min: COVID-19 Pathophysiology Overview Hypothesized

DISCLAIMER: NOT MEDICAL ADVICE. This is a collection of expert opinion largely from first-hand (ie. anecdotal) experiences from MDs in Italy and NYC. As evidence emerges, this information will rapidly become outdated. Some of this information may eventually be found to be incorrect. Do not take any information conveyed in this video as fact. I highly recommend that you watch the webinar where most of this information originates: https://thinkingcriticalcare.com/2020/04/09/covid-19-webinar-respiratory-management-foamed-foamcc/ Some useful resources: EMCrit IBCC Chapter: https://emcrit.org/ibcc/covid19/ Reuben Strayer: https://emupdates.com/cv3w/ FOAMcast: https://foamcast.org/2020/04/08/covid-19-is-it-ards-hape-hemoglobinopathy/ Emergency Medicine News: https://journals.lww.com/em-news/blog/breakingnews/pages/post.aspx?PostID=508 UK Intensive Care Society Statement: https://www.ics.ac.uk/ICS/Pdfs/COVID-19/NECCC_Thematic_Analysis_Summary.aspx Some early literature: Gattinoni L. et al. COVID-19 pneumonia: different respiratory treatment for different phenotypes? (2020) Intensive Care Medicine; DOI: 10.1007/s00134-020-06033-2. Liu, W., & Li, H. COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism. Zhang, Y., Xiao, M., Zhang, S., Xia, P., Cao, W., Jiang, W., ... & Wang, C. (2020). Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19. New England Journal of Medicine. Anecdotes: Peter Antevy on ICU presentations: https://twitter.com/HandtevyMD/status/1246513198490157056 Cameron Kyle-Sidell on avoidance of early intubation in happy hypoxemics: https://twitter.com/cameronks/status/1243582723945566208 Salim Rezaie on HAPE: https://twitter.com/srrezaie/status/1245389444049485832?s=20 George Kovacs on Happy Hypoxemics: https://twitter.com/kovacsgj/status/1245119313515773953 Randy Wax on hypercoagulation: https://twitter.com/drrandywax/status/1247925315038576645