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SciShow's video: The First CRISPR Gene Therapy Is Here

@The First CRISPR Gene Therapy Is Here
CRISPR is a powerful gene editing tool, but its uses have been purely scientific until now. In 2023, US and UK drug regulators including the FDA approved Casgevy, a CRISPR/Cas9-based therapy for sickle cell disease and beta-thalassemia. The FDA also approved a similar treatment, Lyfgenia. Here's how they work. Hosted by: Reid Reimers (he/him) ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Adam Brainard, Alex Hackman, Ash, Benjamin Carleski, Bryan Cloer, charles george, Chris Mackey, Chris Peters, Christoph Schwanke, Christopher R Boucher, DrakoEsper, Eric Jensen, Friso, Garrett Galloway, Harrison Mills, J. Copen, Jaap Westera, Jason A Saslow, Jeffrey Mckishen, Jeremy Mattern, Kenny Wilson, Kevin Bealer, Kevin Knupp, Lyndsay Brown, Matt Curls, Michelle Dove, Piya Shedden, Rizwan Kassim, Sam Lutfi ---------- Looking for SciShow elsewhere on the internet? SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/ TikTok: https://www.tiktok.com/@scishow Twitter: http://www.twitter.com/scishow Instagram: http://instagram.com/thescishow Facebook: http://www.facebook.com/scishow ---------- Sources: https://www.fda.gov/news-events/press-announcements/fda-approves-first-gene-therapies-treat-patients-sickle-cell-disease https://www.gov.uk/government/news/mhra-authorises-world-first-gene-therapy-that-aims-to-cure-sickle-cell-disease-and-transfusion-dependent-thalassemia https://www.ema.europa.eu/en/medicines/human/EPAR/casgevy https://www.statnews.com/2023/12/15/europe-crispr-casgevy-approval-sickle-cell-thalassemia/ https://www.nhlbi.nih.gov/health/sickle-cell-disease https://www.nhlbi.nih.gov/health/sickle-cell-disease/sickle-cell-trait https://www.nhlbi.nih.gov/health/sickle-cell-disease/symptoms https://www.nhlbi.nih.gov/health/sickle-cell-disease/health-effects https://www.nhlbi.nih.gov/health/sickle-cell-disease/treatment https://www.nhlbi.nih.gov/health/sickle-cell-disease/living-with https://www.hopkinsmedicine.org/health/conditions-and-diseases/sickle-cell-disease #:~:text=The%20liver%2C%20heart%2C%20kidneys%2C,Leg%20ulcers https://www.ncbi.nlm.nih.gov/books/NBK526064/ #:~:text=History%20and%20Physical,the%20age%20of%206%20years. https://www.nejm.org/doi/10.1056/NEJMoa2031054 https://www.nejm.org/doi/full/10.1056/NEJMoa2117175 https://www.nejm.org/doi/full/10.1056/NEJMoa2109167 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069474/ https://www.npr.org/sections/health-shots/2019/12/25/784395525/a-young-mississippi-womans-journey-through-a-pioneering-gene-editing-experiment https://www.npr.org/sections/health-shots/2020/06/23/877543610/a-year-in-1st-patient-to-get-gene-editing-for-sickle-cell-disease-is-thriving https://www.npr.org/sections/health-shots/2023/12/25/1219342935/sickle-cell-patients-journey-leads-to-landmark-approval-of-gene-editing-treatmen https://www.npr.org/sections/health-shots/2023/03/16/1163104822/crispr-gene-editing-sickle-cell-success-cost-ethics https://www.yalemedicine.org/news/gene-therapies-sickle-cell-disease https://www.casgevy.com/sickle-cell-disease/treatment-journey https://www.broadinstitute.org/what-broad/areas-focus/project-spotlight/crispr-timeline https://www.broadinstitute.org/what-broad/areas-focus/project-spotlight/questions-and-answers-about-crispr https://www.ncbi.nlm.nih.gov/books/NBK500011/ https://bitesizebio.com/41748/a-beginners-guide-to-lentiviral-transduction/ https://www.casgevy.com/sickle-cell-disease/find-an-ATC https://www.mybluebirdsupport.com/qualified-treatment-center-locator Images: https://www.gettyimages.com/

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This video was published on 2024-03-19 02:30:26 GMT by @SciShow on Youtube. SciShow has total 7.9M subscribers on Youtube and has a total of 3.7K video.This video has received 21K Likes which are higher than the average likes that SciShow gets . @SciShow receives an average views of 303.3K per video on Youtube.This video has received 1.3K comments which are higher than the average comments that SciShow gets . Overall the views for this video was lower than the average for the profile.SciShow #SciShow #science #education #learning #complexly ---------- Sources: https://www.fda.gov/news-events/press-announcements/fda-approves-first-gene-therapies-treat-patients-sickle-cell-disease https://www.gov.uk/government/news/mhra-authorises-world-first-gene-therapy-that-aims-to-cure-sickle-cell-disease-and-transfusion-dependent-thalassemia https://www.ema.europa.eu/en/medicines/human/EPAR/casgevy https://www.statnews.com/2023/12/15/europe-crispr-casgevy-approval-sickle-cell-thalassemia/ https://www.nhlbi.nih.gov/health/sickle-cell-disease https://www.nhlbi.nih.gov/health/sickle-cell-disease/sickle-cell-trait https://www.nhlbi.nih.gov/health/sickle-cell-disease/symptoms https://www.nhlbi.nih.gov/health/sickle-cell-disease/health-effects https://www.nhlbi.nih.gov/health/sickle-cell-disease/treatment https://www.nhlbi.nih.gov/health/sickle-cell-disease/living-with https://www.hopkinsmedicine.org/health/conditions-and-diseases/sickle-cell-disease #:~:text=The%20liver%2C%20heart%2C%20kidneys%2C,Leg%20ulcers https://www.ncbi.nlm.nih.gov/books/NBK526064/ #:~:text=History%20and%20Physical,the%20age%20of%206%20years. https://www.nejm.org/doi/10.1056/NEJMoa2031054 https://www.nejm.org/doi/full/10.1056/NEJMoa2117175 https://www.nejm.org/doi/full/10.1056/NEJMoa2109167 has been used frequently in this Post.

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