Veganius's video: Test de draize - Parce que vous le valez bien Pascal Dash

Ce test est effectué sur le chien ou le singe, mais le plus souvent sur le lapin à cause de la structure de son oeil: il ne peut pas se débarrasser des corps étrangers qui l'obstruent. La tête prisonnière d'un carcan, les yeux du lapin reçoivent des gouttes ou des pulvérisations d'ingrédients chimiques servant à la fabrication de rouge à lèvres ou de shampoing. Pire encore, on maintient parfois, avec des pinces de métal, ses yeux ouverts en permanence. Pendant plusieurs jours, la gravité des lésions oculaires est observée: irritation de la cornée, perforation de l'oeil, démangeaisons et brûlures. The Draize Test is an acute toxicity test devised in 1944 by Food and Drug Administration (FDA) toxicologist John H. Draize. Initially used for testing cosmetics, the procedure involves applying 0.5mL or 0.5g of a test substance to the eye or skin of a restrained, conscious animal, and leaving it for four hours.[1] The animals are observed for up to 14 days, for signs of erythema and edema in the skin test, and redness, swelling, discharge, ulceration, hemorrhaging, cloudiness, or blindness in the tested eye. The test subject is commonly an albino rabbit, though other species are used too, including dogs.[2] The animals are killed after testing.[3] The tests are controversial. They are viewed as cruel by critics, as well as unscientific because of the differences between rabbit and human eyes, and the subjective nature of the visual evaluations. The FDA supports the test, stating that "to date, no single test, or battery of tests, has been accepted by the scientific community as a replacement [for] ... the Draize test" [4] Because of its controversial nature, the use of the Draize test in the U.S. and Europe has declined in recent years and is sometimes modified so that anaesthetics are administered and lower doses of the test substances used.[5] Chemicals already shown to have adverse effects in vitro are not currently used in a Draize test,[6] thereby reducing the number and severity of tests carried out.